Driving time from rocuronium can be used the principle of synchronization, which does not affect the appearance of the time of rocuronium, but induces muscle relaxation, and how pleased t the same anesthesia. But RIP one hour INDICATIVE, painful and severe pain makes the patient piq Re s arm, especially HIF-1 Alpha when rocuronium before unconsciousness was injected Although the pathophysiology of this pain is not yet clear, it may be d activation of nociceptors by osmolality t or pH value of L solution or activation of endogenous histaminekininlike withdrawal movements of inflammatory mediators by rocuronium can adversely affect the patient. Because of the pain and emotional stress may need during the anesthetic, are k Can bronchospasm, asthma, or myocardial infarction induced.
Pretreatment or mixing with a variety of drugs such as opioid Of the lidoca Parts, midazolam, esmolol, thiopental, metoclopramide, baking, ondansetron, or tramadol techniques such as dilution with NaCl. were before, studies in which the lidoca know, found esmolol, bicarbonate, or dilute with drugs A-966492 PARP inhibitor effective in reducing NaCl.were RIP. The lidoca Is the agent most studied and has been very effective in reducing RIP In this study, we have decided that the effect of ephedrine, the rate has not been studied previously, and compare it with the lidoca . do Ephedrine has no analgesic effect. But some m Possible mechanisms have been suggested to induce analgesia. Bradykinin has been reported that mesenteric norepinephrine efflux from sympathetic nerves innervating ends canine pulmonary arteries and inhibit, it was suggested that endogenous noradrenaline released by ephedrine may reduce the effect of bradykinin.
Also TekoL al.reported and improving analgesic effects of opioids Of ephedrine, both experimentally and clinically. , The alpha-adrenergic stimulant effects of ephedra played a R In the intervention group. It has been shown that spinal administration of norepinephrine or produced analgesia in humans and experimental animals. It is postulated that the pain associated with propofol and rocuronium is similar: It seems t immediately after the administration, its short duration and the intensity increases with t following injection. The effect of ephedrine on propofol injection pain was investigated and reported different results. Pretreatment ephedrine has been shown to effectively whichmg in a study by Austin and Parkein TomL ofpropofol ephedrine was used.
In the study by Cheong and pretreatment Aland g kg ephedrine was effective against the pain of propofol injection. However, ephedrine has been reported that at preventing pain during injection of the GCA of propofol in the study Ozkocak et al ineffective in our study, we have decided ephedrine at a dose of GCS, which proved effective against the pain of propofol injection, since no significant adverse h thermodynamic. Like in previous studies, we observed RIP inch of our patients without prior treatment. In our study, the lidoca Was found more effective than ephedrine to relieve RIP Similar to studies by Cheong and al.and Memis and Wongin that rocuronium was also used by the principle of synchronization. RIP is at the patient when the ephedrine pretreatment was applied prevented. Although this percentage was not as high as the lidoca Have pretreatm