The objective of our study is to define the pattern of GB wall thickening for classifying the diagnosis. Methods: Abdominal computed tomography images and pathologic results were obtained from 60 patients who underwent cholecystectomy due to diffuse gallbladder wall thickening were reviewed retrospectively. Enhancement patterns were divided www.selleckchem.com/products/bmn-673.html into 5 types. We compared CT findings with the pathologic results and categorized pathologic findings as inflammatory lesion and tumors. Tumors include adenomyoma, adenomyomatosis, and adenocarcinoma. Results: Enhancement was classified as one of the following five patterns. Type 1 pattern was a heterogeneously

enhancing one-layer gallbladder wall; type 2, strongly enhancing thick inner layer and weakly enhancing outer layer; type 3, borderline enhancement and thickness of the inner layer with small cystic spaces and non-enhancing outer layer; type 4, weakly enhancing thin inner layer and non-enhancing thin outer layer; type 5, weakly enhancing thin inner layer and non-enhancing thick outer layer. Type 1 and 3 showed tendency for tumorous condition but no statistical significance between gallbladder wall enhancement patterns and pathologic causes of diffuse gallbladder wall thickening was noted. PDGFR inhibitor Type;inflammatory lesion;tumor: Type 1;0;3, Type 2;5;1, Type 3;0;2, Type 4;25;2, Type 5;22;0 Conclusion: Analyzing the enhancement

pattern of a diffuse gallbladder wall thickening on CT may helpful in distinguishing gallbladder tumor from benign inflammatory lesion. The study with more patients is needed to confirm this result. Key Word(s): 1. gallbladder; 2. wall thickening; 3. GB ASK1 wall; 4. enhancement Presenting Author: JIN HONG KIM Additional Authors: MIN JAE YANG, GIL HO LEE Corresponding Author: JIN HONG KIM Affiliations: Ajou University Hospital, Ajou University Hospital Objective: Endoscopic

large balloon dilation (EPLBD) using large-diameter balloons (12–20 mm) was introduced to facilitate the removal of large bile duct stones and minimize the need for endoscopic mechanical lithotripsy (EML). Limited data exist on the maximal balloon size that would minimize fatal adverse events associated with EPLBD. In the current study, we aimed to assess the safety profiles of EPLBD according to balloon size and to identify the proper maximal size of a large balloon for treating large bile duct stones. Methods: From March 2004 to July 2013, we retrospectively reviewed the ERCP database system at our center. There were 114 patients in the EPLBD with endoscopic biliary sphincterotomy (EST) group and 165 patients in the EPLBD without EST group. In the EPLBD with EST group, there were 49 patients in the EPLBD with a larger balloon (>15 mm) group and 65 patients in the EPLBD with a smaller balloon (12–15 mm) group.