Data sources: A systematic search was conducted in Medline, Embase, Cochrane Central Register of Controlled Trials, CINAHL, BioMed Central and the Science Citation Index.

Study selection: A total of 191 publications were identified; seven non-randomized studies published between 2004 and 2012 with a total of 945 patients, who underwent laparoscopic right colectomy for malignant and benign disease,

were included in this systematic review.

Intervention: Intra-abdominal versus extra-abdominal confectioning of ileo-coloc anastomosis after right laparoscopic colectomy.

Main outcome measures: Anastomotic leak, overall post-operative morbidity and Tariquidar cost overall 30-days postoperative mortality.

Results: Anastomotic leak rate resulted similar in IA (1.13%) and EA (1.84%) group (P = 0.81, OR of 0.90, 95% CI 0.24-3.10) (Chi(2) Dibutyryl-cAMP = 3.90, P = 0.42, I-2 = 0%). The mortality rate was lower in the IA group (0.34% versus 1.32%), although no statistically difference was demonstrated between the two groups (P = 0.48, OR of 0.52 95% CI 0.09-3.10). It was not possible to conduct a meta-analysis of post-operative morbidity as the data reported in the included studies were too heterogeneous.

Limitations:

The weakness in our results was due to the lack of evidence in current published literature.

Conclusions: The present systematic review of literature and meta-analysis failed to solve the controversies between intracorporeal

and extracorporeal anastomosis after laparoscopic right hemicolectomy. Future randomized, controlled trials are needed to further evaluate different surgical anastomosis after laparoscopic right hemicolectomy. (C) 2012 Elsevier GSK1904529A concentration Ltd. All rights reserved.”
“Public knowledge of, perception of, and attitudes toward epilepsy in Bosnia and Herzegovina (BH) were studied for the first time. One thousand randomly selected adults were asked 12 questions about epilepsy. Ninety-one percent (91%) of respondents had heard about epilepsy, 41% knew someone with epilepsy, 32.5% had witnessed a seizure, and 33.1% did not know any of the symptoms of epilepsy. On average, interviewees were ready to accept a person with epilepsy. Approximately 15% would object if their child played with a child with epilepsy, and 39% believed that a child with epilepsy could not succeed as well as a child Without epilepsy. Although 55.9% would approach a person experiencing a seizure and help, 25.9% would call “”911.”" Positive attitudes correlated with knowing someone with epilepsy and/ or witnessing a seizure. General awareness of and attitudes toward epilepsy in BH approach those of developed countries.