Forty-three adult obese patients, 31 women (72.1%) and 12 men (27.9%), were submitted to electrocardiogram, ergometric test, and echo Doppler cardiogram at presurgical stage and 1 year after Roux-en-Y gastric bypass. The statistical analysis utilized the Wilcoxon, Student’s t, and Shapiro-Wilk tests with 5% significance level.
Weight was reduced from 116.5 +/- 21.5 to 80 +/- 15.9 kg and body mass index from 41.8 +/- 4.4 to 28.4 +/- 3.8 kg/m(2). Cardiac frequency was reduced from BIIB057 purchase 77.9 +/- 9.6 to 70.9 +/- 7.8 bpm, systolic pressure from 130 +/- 20 to 120 +/- 10 mmHg, and diastolic pressure from 80
+/- 10 to 80 +/- 0 mmHg. Ergometric tests showed distance covered from 378.9 +/- 126.5 to 595 Oligomycin A +/- 140.4 m, metabolic coefficient from 6.7 +/- 2.4 to 8.3 +/- 2.6 ml O(2)/kg/min, and oxygen consumption (VO(2)) from 23.1 +/- 8.4 to 30 +/- 10.3 metabolic equivalents of task. The echo Doppler cardiogram showed interventricular septum from 12 +/- 2 to 10 +/- 1 mm, posterior wall from 11 +/- 2 to 10 +/- 1 mm, and ventricular mass from 273 +/- 85 to 216 +/- 60 g. There was improvement in the diastolic function with an increase in the E’/A’ and E/A relationship and the ejection fraction with an increase from 70.2 +/- 7.2% to 72.9 +/- 6.4%.
Bariatric surgery improved physical capacity as well as structural and functional improvement of the heart.”
“Wild and tissue culture raised regenerants
of Artemisia amygdalina, a critically endangered and endemic plant of Kashmir and North West Frontier Provinces of Pakistan were screened for the amount of bioactive principles and in particular antimalarial compound artemesinin. Phytochemical screening of extracts revealed the presence of terpenes, alkaloids, phenolics, tannins (polyphenolics), cardiac glycosides PND-1186 and steroids in wild (aerial, inflorescence) and tissue culture regenerants (in vitro grown plant, callus and green house acclimatized plants). HPLC of Artemisia amygdalina revealed the presence of artemesinin in petroleum ether extracts of wild aerial part, tissue culture raised plant and green house acclimatized
plants. Acetonitrile and water in 70:30 ratios at flow rate of 1ml/min was standardised as mobile phase. Retention time for standard chromatogram was 6.7. Wild inflorescences and callus does not produce artemesinin. This is the first report of phytochemical screening and artemesinin estimation of wild and tissue culture raised regenerants of Artemisia amygdalina.”
“BACKGROUND: To maintain a high standard of patient care, it is essential to provide adequate pain management in patients who undergo nasal surgery. Levobupivacaine and ropivacaine are relatively new long-acting local anesthetics.
OBJECTIVE: The aim of this study was to compare the analgesic effect and blood loss of preincisional levobupivacaine HCl 0.25% and ropivacaine HCl 0.375% in patients undergoing septorhinoplasty.