g. accelerated fetal growth or hydramnios) (diagnosis-group). Methods: A retrospective cohort of 249 patients with GDM treated between 2006 and 2009 were
identified: 74 in the diagnosis-group and 175 in the screening-group. Fetal macrosomia was defined as an abdominal circumference (FAC) >90th percentile at the time of diagnosis of GDM. Large for gestational age (LGA) was defined as a birthweight >90th percentile, corrected for gestational age, parity and sex. Results: GDM was diagnosed 4 weeks later in the diagnosis-group. At diagnosis of GDM, more infants in the diagnosis-group had a FAC >p90 and Fer-1 solubility dmso at birth more infants in this group were LGA. Conclusion: GDM diagnosed by screening is associated with a lower incidence of fetal and neonatal macrosomia than GDM diagnosed by clinical symptoms. A later diagnosis of GDM is more prevalent in presumed low-risk pregnancies. These
results favour a policy of routine screening.”
“SETTING: The tuberculosis (TB) programme in the Sidama zone of southern Ethiopia.
OBJECTIVE: To measure excess mortality in successfully treated TB patients.
DESIGN: In a retrospective cohort study of TB patients treated from 1998 to 2006, mortality was used S63845 Apoptosis inhibitor as an outcome measure, and was calculated per 100 person-years of observation (PYO) from the date of completion of treatment to date of interview if the patient was alive, or to date of death. Kaplan-Meier and Cox regression methods were used to determine the survival and hazard ratios. An indirect method of standardisation was used to calculate the standard mortality ratio (SMR).
RESULTS: A total of 725 TB patients were followed for 2602 person-years: 91.1% (659/723) were alive and 8.9% (64/723) had died. The mortality rate
was 2.5% per annum. Sex, Tariquidar price age and occupation were associated with high mortality. More deaths occurred in non-farmers (SMR = 9.95, 95% CI 7.17-12.73).
DISCUSSION: The mortality rate was higher in TB patients than in the general population. More deaths occurred in non-farmers, men and the elderly. Further studies are required to identify the causes of death in these patients.”
“In the present study, three prenatally detected small supernumerary marker chromosomes (sSMC) were identified by banding cytogenetics and characterized in detail by molecular cytogenetics. In one case an sSMC(10) leading to a pericentric partial trisomy and in two cases heterochromatic sSMC derived from chromosome 22 were characterized. Outcomes were reportedly normal for two of the three cases for whom this information was known.”
“SETTING: All nine public sector hospitals in three districts of Pakistan.
OBJECTIVE: To estimate case notifications of children with tuberculosis (TB) and their outcomes.
DESIGN: A retrospective cohort following all children aged <15 years placed on TB treatment under the National TB Control Programme (NTP) in public hospitals.