Mild or severe CP patients
were older than healthy patients; sex distribution did not vary among groups. Mean presecretin and maximum postsecretin ADCs were higher in healthy patients than in either mild or severe CP groups (P < .01), but did not vary between mild and severe CP groups (P = .25-0.28). An ADC of less than 220 x 10(-5) mm(2)/sec was optimal for delineating between healthy and CP patients.
Conclusion: Pancreatic ADC obtained with DW imaging at 3.0 T prior to secretin administration may help diagnose CP; postsecretin ADC response does not distinguish CP severity. (C) RSNA, 2009″
“Although it is well established that aluminum (Al) is neurotoxic, the potential role of this element in the etiology of Alzheimer’s disease (AD) is not well established. In this study, we evaluated the effects of oral Al exposure on spatial learning, memory
and neurogenesis in Tg2576 mice, an animal model of AD in which Abeta CX-6258 cell line plaques start to be deposited at 9 months of age. Aluminum was given as Al lactate (11 mg/g of food) for 6 months. At 11 months of age a water maze test was carried out to evaluate learning and memory. Subsequently, mice were injected with bromodeoxyuridine (BrdU) and sacrificed 24 hours or 28 days after the last injection in order to assess proliferation, survival and differentiation of neurons. We observed impaired acquisition in the water maze task in Al-treated Tg2576 mice, as well as worse memory in the Al-exposed groups. In terms of neurogenesis, no effects of aluminum were observed
AZD1208 ic50 in proliferation, survival and differentiation. The results of this investigation suggest that Tg2576 mice fed for 210 Selleck EVP4593 days with rodent chow supplemented with Al lactate at 11 mg/g of food have impaired spatial learning although their neurogenesis remains un-modified.”
“The effect of lactosucrose on the short chain fatty acid (SCFA) content, the intestinal flora, the acidity, and the amino nitrogen (NH3-N) content of the intestine in inflammatory bowel disease (IBD) rats was investigated. Dietary lactosucose supplementation increased amounts of beneficial bacteria and diminished amounts of pathogenic bacteria. Lactosucrose decreased the NH3-N content in cecal and colonic digesta, compared to inflammatory rats. Lactosucrose increased the acidity in the intestinal lumen, and the acetic acid, propionic acid, and butyric acid contents in cecal and colonic digesta, compared to inflammatory rats. The butyrate content in the lactosucrose group was higher than for the inflammatory, sulfasalazine, and normal groups. Lactosucrose promoted beneficial intestinal health and prevented intestinal inflammation.”
“The mechanical properties including hardness, Young’s modulus, and fracture toughness of heavily phosphorus (P)-doped Czochralski (Cz) silicon have been investigated by means of nanoindentation and microindentation.