Only the outcome ‘poor response’ was studied and no significant differences were found at 5-weeks follow-up. Five recent RCTs that studied interventions after an RCR were found. A low-quality RCT (Klintberg et al., 2009) compared progressive physiotherapy (i.e. early loading of the rotator cuff (active and passive motion)) to traditional physiotherapy (i.e. immobilization of 6 weeks followed

by only passive motion). Only the progressive group showed significant within group results on the pain Romidepsin cost outcomes at 12 and 24 months follow-up. However, no comparisons between the groups were made. A high-quality study (Michael et al., 2005) compared RCR and CPM plus physiotherapy with RCR and physiotherapy alone. ROM (90° active abduction of the shoulder) was managed after 31 days in the CPM plus physiotherapy group compared to 43 days in the physiotherapy alone group (p = 0.292). Another high-quality study of Hayes www.selleckchem.com/products/sorafenib.html et al. (2004) compared individualized physiotherapy

to a standardized home exercise program after RCR and found no significant differences between the groups for any passive ROM, muscle force or overall shoulder status at 12- and 24-weeks follow-up. A low-quality study (Roddey et al., 2002) compared two instructional approaches to a home exercise program after RCR: a videotape versus personal instruction by a physiotherapist. No differences between Pyruvate dehydrogenase lipoamide kinase isozyme 1 the treatment groups were found on the Shoulder Pain and Disability Index (SPADI) and UPenn Shoulder Scale at 12-weeks, 24-weeks and 1-year follow-up. A low-quality RCT (Blum et al., 2009) studied the effectiveness of Repetitive H-Wave device stimulation (HWDS) versus placebo HWDS and

found significant within group results for both groups for external rotation (arm at slide) and internal rotation (arm at 90°) at 90 days follow-up; the HWDS group improved most. No significant within group results were found for the other ROM measurements. No comparisons were made between the groups. We found no evidence for the effectiveness of progressive compared to traditional physiotherapy, in the long-term or for the effectiveness of CPM as additive to physiotherapy after RCR. Furthermore, we found no evidence for the effectiveness of splinting in abduction versus resting the arm at the side, physiotherapy versus a standardized home exercise program, instructional approaches versus a home exercise program (videotape), or H-wave device stimulation versus placebo after RCR. This study focused on the effectiveness of non-surgical and surgical interventions for treating RotCuffTears not caused by acute traumata or systemic diseases. Neri et al.