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“Purpose: We assessed whether a surgeon self-graded assessment of neurovascular bundle preservation quality predicted PCI-32765 datasheet potency following laparoscopic radical prostatectomy.
Materials and Methods: From April 2001 to January 2007 a total of 767 laparoscopic radical prostatectomies were. performed by 2 surgeons who graded left and right neurovascular bundle sparing qualities on a scale of 0 to 5. The total number of nerves spared
was also recorded. We defined a composite variable, the bilateral sum neurovascular bundle sparing score, to encode 1 independent variable (scale of 0 to 10) for analysis. Multivariate linear regression models were evaluated to assess the significance of the bilateral sum neurovascular bundle sparing score for predicting validated potency outcomes, controlling for significant clinical
variables in preoperatively Alpelisib cell line potent men (Sexual Health Inventory for Men 21 or greater). The bilateral sum neurovascular bundle sparing score based model was compared to a model based on the separate number of nerves spared.
Results: A total of 313 patients were preoperatively potent, of whom 226 (72%), 77 (25%) and 10 (3%) underwent bilateral, unilateral and no neurovascular bundle sparing, respectively. Of the men who underwent bilateral neurovascular bundle sparing 64.3% were engaging in intercourse by 1 year. Regression models indicated that the bilateral sum neurovascular bundle sparing score and the number of nerves spared were highly significant independent positive predictors of postoperative sexual function (p <0.001). The bilateral sum neurovascular bundle sparing score model provided differential prognostic
information in the majority group that underwent bilateral nerve preservation. Other independently predictive variables were Axenfeld syndrome patient age at surgery, months since surgery and preoperative Sexual Health Inventory for Men 21 to 25 (each p <0.001).
Conclusions: Cavernous nerve preservation during laparoscopic radical prostatectomy is not an all or none phenomenon. A surgeon subjective sense of neurovascular bundle sparing quality may aid in accurately characterizing the return of sexual function following laparoscopic radical prostatectomy. Partial nerve preservation may lead to an incremental improvement in the return of sexual function.”
“Purpose: The aim of this study was to assess the relationship between prenatally diagnosed nonrefluxing hydronephrosis and urinary tract infection.
Materials and Methods: We reviewed patients who were born at our institution between March 1989 and February 2006. Those who were diagnosed with fetal hydronephrosis confirmed on postnatal sonography were enrolled in the study. Hydronephrosis was graded according to the Society for Fetal Urology classification. Obstructive uropathy was diagnosed with (99m)technetium mercaptoacetyltriglycine renal scan and clinical courses. Voiding cystourethrography was done to exclude patients with vesicoureteral reflux.