Results:
Coronary arteriography revealed that 3 rabbits (3/10) in the BSA group had various levels of dilation and narrowing of the left coronary arteries, while histological examination showed that 10 rabbits (10/10) had infiltration of the coronary arteries by inflammatory cells. Incomplete endothelium, breakage of elastic fiber, and intimal thickening were also observed in 8 rabbits (8/10) from the BSA group. Ultrastructurally, in 3 rabbits (3/10) in the BSA group, leukocyte learn more migration, shedding of endothelial microparticles from the plasma membranes, incomplete endothelium, abscission of endothelial cells, breakage of the internal elastic lamina (IEL), degeneration of smooth muscle cells in the medial membrane, and swollen mitochondria were detected. By contrast, the IEL of the NS control group was continuous and of uniform thickness.
Conclusion: This rabbit model of coronary arteritis displayed histopathological and ultrastructural features similar to those of Kawasaki disease in humans. Breakage of the IEL, a key factor in aneurysm formation, was observed
in the coronary arteries. selleck Therefore weanling rabbits may serve as an experimental model for immune complex vasculitis involving coronary arteries that mimics Kawasaki disease.”
“Background: With improvements in technology, renal biopsies have become safer and could potentially be effectively carried out in the outpatient setting. The purpose of our study is to compare the safety and cost of performing outpatient versus inpatient renal biopsies at a single Northern California pediatric hospital.
Methods: We retrospectively studied the records of patients who underwent renal biopsy at our hospital during the period June 2001 to June 2006. Patients who were admitted to the hospital were compared with those who underwent biopsy as outpatients and were observed postprocedure for 4 hours for complications.
Results: 54 patients underwent 60 biopsies as inpatients and 58 patients underwent 78 biopsies as outpatients. Two inpatients required intervention for bleeding. One patient in the outpatient
group was readmitted for persistent gross hematuria that subsided without intervention, and another patient had an inadequate sample obtained. Considering physician, nursing and ancillary hospital charges for the inpatient stay, the difference in cost PD173074 inhibitor was US $4,133 per procedure.
Conclusions: Our study suggests that discharging patients after a 4-hour monitoring period is a safe practice in a select group of patients. This practice has profound financial advantages by reducing health care costs and potentially improves patient satisfaction.”
“BACKGROUND: Obturator nerve injury may occur in gynecologic surgery, particularly in cases in which extensive pelvic sidewall retroperitoneal dissection is performed. The lack of tactile feedback from the robotic surgical system may contribute to obturator nerve injury.