We present two cases of patients with intractable supplementary motor

area seizures investigated with video/EEG monitoring. Their postictal EEG records revealed an immediate postictal recovery of alpha activity, mimicking the pattern seen with psychogenic nonepileptic seizures. Prolonged video/EEG Navitoclax mw monitoring is mandatory in establishing the diagnosis of supplementary motor area seizures and in distinguishing this condition from nonepileptic seizures. Published by Elsevier Inc.”
“Objective: Epidemiological studies suggest a relationship between midlife metabolism and old age cognition. We examined the effect of midlife BMI and related metabolic conditions on old age cognitive performance and whether there was evidence from direct causal pathways behind these associations in a large sample of Finnish twins. Design: Midlife variables of 2606 twin individuals were based on postal questionnaires and registry records. Old age cognitive status was measured by using a validated telephone interview. Results: Midlife BMI, cardiovascular disease, hypertension and diabetes were each associated with old age cognition when adjusted for sex, education, birth year and age at the interview. Similarly, overweight increased

the risk for categories of mild impairment of cognitive function and likely dementia. Cardiovascular disease diminished the mean cognitive score also among discordant twin pairs (beta-estimate=1.10, p-value=0.012). signaling pathway Weight gain more than 1.7 kg/m(2) and loss more than 2 kg/m(2) within an average of 5.6 years were associated

with lower cognitive performance independently of BMI. An additive genetic correlation explained the association between BMI and old age cognition (r(A)(-)=-0.12, 95% CI -0.21; -0.03), but adjustment for education led to loss of significance (r(A)=-0.06, 95% CI -0.16; 0.03). Conclusions: Midlife metabolic diseases, especially diabetes, are independently associated with impaired cognition in old age. Even a more subtle weight change than suggested previously was associated with lower old age cognition. There was evidence from direct causal pathway between cardiovascular disease and LY3023414 old age cognition, while the correlation between midlife BMI and old age cognition was explained mostly by genetic factors.”
“Rock-salt NiO and Ni(0.7)Zn(0.3)O nanoparticles were investigated by x-ray diffraction, atomic-force microscopy, and magnetic measurements. Nanoparticle diameters varied from 8 to 30 nm depending on reaction conditions. There are two main magnetization contributions, the field-induced spin canting of the antiferromagnetic sublattices and the magnetization rotation caused by uncompensated spins interacting with the magnetic field.