Cholangioscope-directed forceps biopsies have a much higher sensi

Cholangioscope-directed forceps biopsies have a much higher sensitivity in most reports, but are usually negative in some cases of sclerosing-type cholangiocarcinoma. EUS-FNA is the best method for cytologic diagnosis of distal tumors, however for proximal tumors, specially those that are not mass-forming, traditionally the sensitivity is much lower Methods: As part of a prospective study to compare methods for the diagnosis of indeterminate biliary strictures in a stepwise-fashion, EUS-FNA

is performed initially when technically feasible, followed by ERCP with brushings and cholangioscopy with forceps biopsies. Only when FNA is inadequate or unknown during the procedure (no cytologist present), the other procedures are performed selleck during ERCP. Results: 42 patients have been included, of which 19 had proximal strictures. Of these, EUS-FNA was performed in 17 with a 94% sensitivity (in two it was technically impossible, for brush cytology the sensitivity was 55% (5/9) and 30% for cholangioscopy directed biopsies (2/6). 18 tumors were of the sclerosing, non-mass forming type, seen by EUS only as diffuse thickening of the wall and no intralumenal mass bu cholangioscopy. Conclusion: An approach MK2206 starting with EUS-FNA seems highly sensitive in cases of non-mass forming proximal strictures and obviates the need for other procedures; this is a change in the traditional IKBKE paradigm

in these patients. Key Word(s): 1. cholangiocarcinoma; 2. EUS-FNA; 3. cholangioscopy; 4. cytology; Presenting Author: HUIJER HWANG Additional Authors: RAUL MATANO, MARTIN GUIDI, JULIO DE MARIA, ESTEBAN PROMENZIO, FERNANDO RAGONE, JUAN VISCARDI Corresponding Author: HUIJER HWANG Affiliations: El Cruce Hospital Objective: Approximately 10-15% of the choledocal stones extraction can be difficult with ERCP conventional sphincterotomy. In the past decade it has begun to use a new technique combining sphincterotomy with large balloon dilation of 12-20 mm in diameter in such cases: larger than 20 mm stones extraction , multiple stones, large periampullary diverticulum and / or thin distal common bile duct.

Several studies have demonstrated increased therapeutic efficacy and lower complication rates. Aim:To compare the effectiveness and complications of sphincterotomy followed by large balloon dilation with sphincterotomy alone in the management of difficult bile duct stones (giants and / or multiple calculies). Methods: A retrospective comparative analysis of managing difficult stones (stones &gt 20 mm in diameter and / or multiple) by ERCP for 26 months. Comparison of the first treatment with conventional ERCP between sphincterotomy (group A) and sphincterotomy plus large balloon dilation (group B) was made, and the following variables were analized: procedural success, successful complete removal of the stones, use of mechanical lithotripsy and complications.

At the site-specific scale, den sites were associated with steep,

At the site-specific scale, den sites were associated with steep, rugged terrain with bare rock. At the home-range and landscape scales, den sites were placed in rugged terrain at 1100 m a.s.l. and away from infrastructure (private roads and public roads). These features provide snowdrifts into which wolverines can excavate dry, safe cavities. Den sites were STA-9090 manufacturer also placed

away from infrastructure, indicating that den-site distribution, and possibly successful reproduction, may be partly influenced by human activities. Recurrent use of specific topographic features may provide valuable information for guiding geographically differentiated management and monitoring efforts, and augmenting recovery of endangered wolverine populations. “
“The ‘dear enemy phenomenon’ (DEP) is a form of neighbour–stranger discrimination in which resident territorial individuals respond less agonistically to

intrusions by known neighbouring conspecifics than they do to strangers. We tested philopatric female yellow-bellied marmots (Marmota flaviventris) for the presence of DEP. We hypothesized that dominant females discriminated between the anal gland secretion (AGS) from female selleckchem neighbours and strangers, and predicted that they would respond more agonistically (as reflected by the duration of both sniffing and physical behaviour) towards AGS from strangers than neighbours. We also hypothesized that female marmots would respond differently to kin and non-kin female neighbours, and predicted a reduced agonistic response to related individuals. Direct observations of resident marmot’s responses to the olfactory trials showed that marmots spent significantly longer durations sniffing the AGS of both neighbours and strangers than a neutral scent-free control. However, there was no significant difference in the sniffing response duration towards AGS from a neighbour or a stranger. In addition, kinship

was not found to influence the responses of residents to neighbours or strangers. We conclude that, although female yellow-bellied marmots detect AGS, they do not seem to discriminate between neighbours and strangers via AGS scent marks. Other Interleukin-2 receptor secretions may be used in territorial identification. “
“Land conversion in Mediterranean Europe has substantially altered the biotic interactions and patterns of resource availability in many ecosystems with serious environmental consequences on some species. Habitat changes are thought to be the main cause of the decline in numbers of European hares, Lepus europaeus, throughout Europe. In contrast, the Iberian hare L. granatensis, in Spain has significantly increased in numbers since the early 1990s. We aimed to investigate changes in habitat favourability of the Iberian hare within municipalities in southern Spain from 1960s to the 1990s.

Conclusions — The available

Conclusions.— The available Talazoparib cost evidence suggests that naproxen sodium is more effective but may cause more adverse events than placebo in the acute treatment of moderate to severe migraine. It is effective in reducing headache intensity, rendering pain-free at 2 hours

and improving migraine-associated symptoms. However, its effectiveness relative to other active comparators needs to be better defined by appropriate head-to-head clinical trials. “
“To evaluate the geographic location of the United Council for Neurologic Subspecialties (UCNS)-certified headache subspecialists as compared with ratios of expected migraine and chronic migraine populations in the United States. The UCNS is a professional medical organization that accredits fellowship programs and certifies physicians who demonstrate MK-1775 price competence in various neurologic

subspecialties, including headache medicine. There are a limited number of UCNS-certified headache subspecialists currently practicing in the United States. All of the UCNS-certified headache subspecialists were geographically located and compared with demographic data about state populations obtained from the U.S. Census. The expected migraine and chronic migraine populations were calculated for each state based on recently published epidemiologic data. Ratios of UCNS-certified headache subspecialists to expected migraine and chronic migraine populations were compared for each state. These data were then organized by U.S. Census region and division. As

of the 2012 examination cycle, 416 UCNS-certified headache subspecialists are currently practicing in the United States. The states with Histidine ammonia-lyase the highest number of headache subspecialists include New York, California, Ohio, Texas, Florida, and Pennsylvania. Six states have zero headache subspecialists, eight states have one headache subspecialist, and five states have two headache subspecialists. As per the U.S. Census, the total U.S. population for ages 12 years and older is 259,908,563. The total expected migraine population (11.79% of the general population) for ages 12 years and older is 30,594,362. The total expected chronic migraine population (0.91% of the general population) for ages 12 years and older is 2,361,397. The states with the best ratios of headache subspecialists to expected migraine and chronic migraine populations include the District of Columbia, New Hampshire, New York, and Nebraska. Besides states with zero headache subspecialists, the states with the worst ratios of headache subspecialists to expected migraine and chronic migraine populations include Oregon, Mississippi, Arkansas, and Kansas. When organized by U.S. Census regions, the Northeast has the best ratios of headache subspecialists to expected migraine and chronic migraine populations, while the West has the worst ratios of headache subspecialists to expected migraine and chronic migraine populations. In terms of U.S.

When stratified by HBe positivity, although IL-22 was still signi

When stratified by HBe positivity, although IL-22 was still significantly associated with a VR, the number of patients was only 20 in this study. Further research is needed to clarify the association between IL-22 and treatment response. Lastly, we uncovered that lower baseline serum HBsAg and HBcrAg levels were associated with a VR. HBcrAg assays measure serum levels of HB core, e and 22-kDa precore antigens simultaneously using monoclonal antibodies that recognize the common epitopes of these three denatured antigens.[35] Because this assay

measures all antigens transcribed from the precore/core gene, it is regarded as core related.[36] The AUC values for baseline HBsAg and HBcrAg levels were high at 0.838 and 0.858, respectively. Several studies have shown that HBsAg is useful for the management of ETV BGJ398 solubility dmso therapy,[37, 38] whereby an HBsAg decline is most profound in patients losing HBeAg detectability during treatment.[39] HBeAg positivity was also significantly associated with treatment outcome in the present study. However, because HBcrAg, but not HBsAg or HBeAg, was an independent factor related to a VR in multivariate analysis, our results indicated that serum HBcrAg quantitation may offer clinicians a

new tool in predicting treatment outcome in HBV infection. Further investigation of large cohorts must be done to validate the significance of our findings. With a VR at 12 months established as a parameter, 38 patients (79%) achieved this event. ALK inhibitor Serum IL-22, HBsAg and HBcrAg levels were all still significantly associated with a VR at 12 months. AUC values were as high as between 0.737 (IL-22) and 0.878 (HBcrAg). Galactosylceramidase Furthermore, ALT normalization was achieved in 40 (83%) and 42 (88%) patients at 12 and 24 months, respectively. Although lower median pretreatment levels of HBsAg and HBcrAg were significantly associated with ALT normalization, there was no such statistically significant relation for IL-22 (data not shown). In summary, a cytokine

(IL-6) and several chemokines (CCL2, CXCL9 and CXCL10) were seen to be elevated in patients with chronic hepatitis B. Our results indicate that serum IL-6 and CXCR3-associated chemokines are correlated with liver injury, serum IL-22 is a useful biomarker for predicting a VR to ETV therapy, and a lower level of serum HBcrAg is related to a favorable response to antiviral therapy. This research was supported in part by a research grant from the Ministry of Health, Labor, and Welfare of Japan. The authors thank Yuki Akahane, Asami Yamazaki and Toyo Amaki for their technical assistance, and Trevor Ralph for his English editorial assistance. Table S1 Demographic, clinical characteristics, and serum cytokines and chemokines in patients with hepatitis B e-antigen (HBeAg) positive and hepatitis B e-antigen (HBeAg) negative patients.

Disclosures: John P Sabo – Employment: Boehringer Ingelheim Phar

Disclosures: John P. Sabo – Employment: Boehringer Ingelheim Pharmaceuticals, Inc. Benjamin Selleck SP600125 Lang – Employment: Boehringer Ingelheim Pharma GmbH & Co. KG Mabrouk Elgadi – Employment: Boehringer Ingelheim Fenglei Huang – Employment: Boehringer Ingelheim Pharmaceuticals, Inc Aim: To evaluate the effect of faldaprevir at steady-state on the pharmacokinetics

and pharmacodynamics of methadone or buprenorphine/naloxone in subjects on stable opioid maintenance therapy. Methods: This was an open-label study in subjects receiving a stable dose regimen of methadone (up to a maximum of 180 mg/day) or buprenorphine/naloxone (up to a maximum of 24 mg/6 mg per day). On Day 2, subjects received 480 mg faldaprevir (loading dose) followed by 240 mg QD faldaprevir on Days 3 to 9. Blood samples were taken on Days 1 and 9 for pharmacokinetic analysis for methadone and buprenorphine/naloxone (up to 24 h post-dose) and faldaprevir (up to 96 h post-dose). Pharmacodynamics of the opioid

maintenance regimens were evaluated by the objective Seliciclib in vivo opioid withdrawal scale (OOWS) and subjective opioid withdrawal scale (SOWS). Results: Thirty four subjects entered and completed the study; 15 on methadone, 19 on buprenorphine/naloxone. Co-administration of faldaprevir with methadone or buprenorphine/naloxone resulted in geometric mean ratios for AUC0-24,ss″, Cmax,SS

and C24,SS of si.2 for R-methadone and S-methadone, and ≤1.1 for buprenorphine and naloxone (Table 1). Similar faldaprevir exposures were observed in both the methadone and buprenorphine/naloxone treated subjects. There was no evidence of symptoms of withdrawal as evaluated by the validated OOWS or SOWS scores following co-administration of RVX-208 faldaprevir with methadone or buprenorphine/naloxone. Conclusions: No dose adjustment is required for methadone or buprenorphine/naloxone when co-administered with faldaprevir. Disclosures: Michael J. Schobelock – Employment: Boehringer Ingelheim Pharmaceuticals Inc. Lynn R. Webster – Advisory Committees or Review Panels: AstraZeneca, Boehringer Ingelheim, Covidien Mallinckrodt, Nektar Therapeutics, Orexo; Consulting: CVS Caremark, Jazz Pharmaceuticals, Neura Therapeutik, Quintiles, Ther-avance Mabrouk Elgadi – Employment: Boehringer Ingelheim Fenglei Huang – Employment: Boehringer Ingelheim Pharmaceuticals, Inc The following people have nothing to disclose: David Joseph, Robert A. Riesen-berg, Bradley Vince, Abidemi Adeniji Background: Peginterferon Lambda-1a (Lambda), a Type III interferon (IFN), exerts potent antiviral activity through a unique receptor complex with limited cellular distribution outside the liver, and is expected to have a differentiated safety profile compared to peginterferon alfa (alfa).

When hHpSTCs were plated onto culture plastic and in KM supplemen

When hHpSTCs were plated onto culture plastic and in KM supplemented with 5% fetal bovine serum, they were activated into the cells with a myofibroblast phenotype emerging within 3 to 5 days

of culture (Supporting Information Fig. 3). The cells were even longer (up to 50 μm or longer), had a centrally located nucleus, and expressed the highest levels observed for ICAM1, ASMA, and desmin. We surveyed the biological activities of numerous mesenchymal cell lines and primary cultures of mesenchymal cells as feeders (Supporting Information Table 4). We eventually realized that even transient exposure to serum resulted in muting of the distinctions in paracrine signals produced by the different mesenchymal cell subpopulations and their skewing toward biological activity typical for fibrosis or cirrhosis. Therefore, a serum-free medium for mesenchymal cells (MCM) was developed (Supporting Information Fig. 1) that enabled us to define feeder effects and the paracrine signals produced with freshly immunoselected mesenchymal cell subpopulations from fetal human livers versus adult human livers under serum-free conditions in short-term cultures (up to 2 weeks). Using this strategy, we determined that all the mesenchymal subpopulations produced multiple types of collagens, basal adhesion molecules, selleck chemicals llc proteoglycans, and elastin but at quite different levels

(Fig. 1E and Table 1). The angioblasts (CD117+/KDR+ or CD133+/KDR+) from fetal livers produced less matrix than any of the tested mesenchymal cell subpopulations, produced low levels of type III, IV, and V collagens (only type III was detectable by immunohistochemistry), laminin A4 but not the other laminins or fibronectin, chondroitin sulfate proteoglycans (CS-PGs) and low levels of syndecan (only

CS-PGs were detected by immunohistochemistry), and HAs. Those from adult livers produced higher levels of syndecan, laminin A4, fibronectin, and type IV collagen. Fetal liver–derived endothelial (CD-31+) cells made all of the forms of heparan sulfate proteoglycans (HS-PGs), type I, III, and V collagens (but not type IV collagen), low levels of laminin B2 and fibronectin, and elastin. Adult liver–derived endothelial cells (CD-31++) made high levels of HS-PG2 and syndecan, type I and IV collagens, laminins A4 and B3, fibronectin, Org 27569 and elastin. In summary, the matrix chemistry in angioblast and endothelial subpopulations was dominated by HS-PGs and some but not all laminin forms, and there was a significant increase in elastin with development. The stellate cell subpopulations produced the highest amounts of most of the analyzed matrix components, expressed low or negligible levels of laminins, strongly expressed fibronectin and elastin, and were high producers of all the collagens (especially type I) and the CS-PGs. As for the angioblast and endothelial cell subpopulations, the levels were highest in those from adult livers. Supporting Information Fig.

Initially, this commences with closed chain (weight-bearing type)

Initially, this commences with closed chain (weight-bearing type) such as squats, leg press, step-ups, elliptical trainer and stationary bike. Patients are encouraged to progress towards functional goals. Occasionally, (and dependent on the particular patient) open chain exercises such as seated knee extension may be utilized to promote further quadriceps strength. There is no predefined length of rehabilitation input. It is always based on the individual at hand and may vary between patients, depending on other comorbidities. Ultimately, the availability of clotting factor concentrate permits intensive physiotherapy to be an expectation for patients who present with stiff knees after surgery.

By ‘correcting’ the bleeding tendency, even for a short time, rehabilitation selleck screening library for these patients can be viewed in the same thread as those presenting without a bleeding disorder. Tremendous progress has been made over the past century in the diagnosis, treatment and rehabilitation of people with haemophilia. But even with the advent of medical progression many issues still remain unsolved regarding management of this condition, especially in countries with resource constraints. Prophylaxis and/or synoviorthesis

should be implemented to delay the progression of joint damage and strict follow-up is recommended to choose the best surgical Palbociclib price approach when necessary. Moreover, patients should be informed of the risk-benefit ratio of each surgical procedure taking into account functional improvement, quality of life amelioration and risk of complications. In the light Sodium butyrate of these considerations, patients with haemophilia represent a challenge for orthopaedic specialists, because in comparison with the general population they have different surgical indications, require

different surgical techniques, need dedicated postoperative care and more frequently develop complications. Hence, the contribution of skilled orthopaedic surgeons and physiotherapists is crucial to achieve good outcomes. The authors stated that they had no interests which might be perceived as posing a conflict or bias. “
“Summary.  It is not clear whether von Willebrand disease (VWD) is associated with an increased risk of postpartum haemorrhage (PPH). We assessed the effect of VWD on PPH in a case-control study. Logistic regression was used to test for differences in the odds of PPH in deliveries to women with and without VWD, before and after adjustment for known risk factors. A total of 62 deliveries in 33 women with VWD were compared with controls matched for age, year of delivery and parity. Primary PPH was observed in 12/62 (19.4%) deliveries in women with VWD and 16/124 (12.9%) controls. The unadjusted odds ratio (OR) for VWD as a risk factor for PPH was 1.62 (95% CI 0.75–3.49, P = 0.22). After adjustment for other risk factors for PPH, the OR for VWD as a risk factor for PPH was 1.31 (95% CI 0.48–3.

22% of gastric cancers are HER-2 positive Therapy targeting HER-

22% of gastric cancers are HER-2 positive. Therapy targeting HER-2 oncogene with the monoclonal antibody trastuzumab (Herceptin) is prohibitive in our country due to high costs. Methods: Case description:

Patient of 41 years presented with a diagnosis of stage IV gastric adenocarcinoma, documented in July 2012 based on following criteria: clinical (abdominal pain), endoscopic (infiltrative tumor of 4-5 cm on the greater curvature), histology (tubulo-papillary adenocarcinoma, GII, infiltrative) imaging (CT infiltrative tumor 5.5/4 cm on the greater curvature invading the pole of the spleen, liver and multiple peritoneal metastases). He made 8 cycles of polychemotherapy in Milan, with EFC (Epirubicin, 5-Fluorouracil, Cisplatin), with documented disease progression in October 2012 by TC: increasing spleen infiltration, increased size of liver metastases, new liver lesions. He came for begging of salvage therapy. We performed immunohistochemistry of gastric biopsies documenting HER-2 status: 3+. We initiated therapy with Docetaxel and, given the patient’s young age, Transtuzumab (Herceptin) from his own resources. Results: Evaluation after 5 cycles of docetaxel and

4 cycles of Herceptin (April AZD8055 cost 2013) documents the following: the almost complete morphologic remission of the gastric tumor and mesenteric determinations; morphological and numerical remission of liver and spleen injuries. Patient continues Herceptin with a new evaluation in 3 months time. Conclusion: This patient is, the first from the Oncologic Registry Bihor treated with Herceptin who went into almost complete remission, despite disease progression after first-line

therapy, thanks to administration of Herceptin, underlining the importance of both standardization of immunohistochemical assessment for HER2 overexpression in all patients with gastric cancer and of obtaining financial resources for Herceptin biological tratament. Key Word(s): 1. gastric cancer; 2. her-2; 3. transtuzumab; Presenting Author: YUN SHAO Additional Authors: WEIHAO SUN Corresponding Ureohydrolase Author: WEIHAO SUN Affiliations: the first affiliated hospital with nanjing medical university Objective: The specific cyclooxygenase (COX)-2 inhibitor have the anti-proliferative and pro-apoptotic effects on gastric cancer cells. There are somerandomized, double-blind, placebo-controlled trials with COX-2 inhibitors (coxibs) showing an increased rate of thrombotic vascular events in patients treated with coxibs. Ursolic acid (UA), a natural pentacyclic triterpenoid carboxylic acid, is largely distributed in medical herbs. UA has a wide range of anticancer functions such as proapoptosis, antiangiogenesis, antimetastasis and cytotoxicity in stomach, liver, lung and bladder cancers.

The dose response observed with conditioned media suggests that a

The dose response observed with conditioned media suggests that activation of TLR9 requires a threshold concentration of DNA. The endosomal location of TLR9 has been shown to be a critical determinant in regulating the discrimination between self and nonself DNA.28 However, under certain conditions intracellular TLR9 has also been shown to respond to DNA molecules traditionally considered inactive. At high concentrations, DNA strands that lack canonical CpG motifs, contain phosphodiester bonds, and structurally resemble endogenous mammalian DNA can become immunostimulatory and trigger TLR9-dependent cytokine production.12, 40 In addition, necrosis

itself may induce modifications in endogenous DNA that could potentially increase its binding or activation of TLR9. It is therefore this website conceivable that in situations such as liver I/R, in which there is extensive uncontrolled necrosis, the host’s ability to control cell death is overwhelmed,

resulting in a dysregulated inflammatory response. HMGB1 is well recognized for its role as a DNA-binding protein that is passively released after necrosis.8, 41 HMGB1 also has been shown to exert its pro-inflammatory effect through multiple pattern-recognition receptors, including TLR9.13, 38 In liver I/R, the failure of anti-HMGB1 to confer additional protection to TLR4−/− mice suggests that during hepatic inflammation HMGB1 acts predominantly through TLR4.7 We found no difference in neutrophil TLR4 expression between WT and TLR9−/− mice before or after I/R (unpublished data). Although the functional outcome and signaling cascades that result from single TLR blockade are well described, the intricacies selleck compound of signaling when multiple pathways are blocked remain unclear. Our data reveal that maximal cytokine suppression and increased resistance to hepatic ischemia can be achieved when both TLR9 and HMGB1 signaling are absent. These results confirm that DNA and HMGB1 play nonredundant roles as DAMPs in liver I/R as they promote inflammation and neutrophil-mediated collateral damage. Our data show that TLR9−/− mice regulate local and systemic inflammation after

liver I/R via impaired neutrophil function. Although the use of iCpG to block a crucial Montelukast Sodium DAMP pathway might serve as a therapeutic option in the treatment of liver I/R, blockade of multiple pathways can limit injury further. Understanding the role and interplay between pattern recognition receptors on immune cells may create novel and more innovative approaches to dealing with a variety of conditions associated with I/R. “
“Cholangiocarcinoma (CCA) cells paradoxically express the death ligand, tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) and, therefore, are dependent upon potent survival signals to circumvent TRAIL cytotoxicity. CCAs are also highly desmoplastic cancers with a tumor microenvironment rich in myofibroblasts (MFBs). Herein, we examine a role for MFB-derived CCA survival signals.


Ian KU-60019 cost Lisman, Ton Liu, Jianguo Liu, Lin Liu, Zhang-Xu Llovet, Josep Lo Re, Vincent Locarnini, Stephen Locker, Joseph Loftis, Jennifer Loguercio, Carmela

Lohmann, Volker Lok, Anna Lok, Anna S.F. Lomas, David Loomba, Rohit Loomes, Kathleen Loren, David Lu, Shelly Lu, Xuanyong Lutsenko, Svetlana Luyendyk, James P. Machida, Keigo Maeda, Shin Maekawa, Shinya Maher, Jacquelyn Maini, Mala Majno, Pietro Major, Marian Malejczyk, Jacek Malhi, Harmeet Malik, Ahsan Mandrekar, Pranoti Mangia, Alessandra Mann, Derek Manns, Michael Manos, M. Michele Mantovani, lorenzo Marche, Patrice Marchesini, Giulio Marelli-Berg, Frederica Marin, Jose Marquardt, Jens Marra, Fabio Marrero, Jorge Mars, Wendy M. Martin, Paul Marzioni, Marco Mathivanan, Suresh Mathurin, Phillippe Mato, José Matthews, Gail Mazzaferro, Vincenzo McClain, Craig McClain, Donald McDiarmid, Sue McGill, Mitchell McGlynn, Katherine GDC-0980 McKeating, Jane A McKeehan, Wallace McMahon, Brian

Mehal, Wajahat Meisgen, Florian Mells, Jamie Meloni, Franca Meng, Fanyin Merion, Robert Merkel, Carlo Merli, Manuela Meuleman, Philip Michalak, Thomas Michalopoulos, George Mieli-Vergani, Giorgina Milich, David Mishra, Lopa Missale, Gabriele Mistry, Pramod Mita, Eiji Mitchell, Donald Mitchell, Kisha Mitchell, Mack C. Miura, Kouichi Miyajima, Atsushi Mizuguchi, Hiroyuki Moller, Soren Molleston, Jean Molloy, Jeffrey Monga, Satdarshan Montagnese, Sara Montoliu, Carmina Moore,

David Moore, David Moore, Derek Moore, Kevin Moreau, Richard Mori, SDHB Masaki Moriggl, Richard Morishima, Chihiro Moschen, Alexander Moschetta, Antonio Moucari, Rami Moustafa, Tarek Moylan, Cynthia Muenz, Christian Mufti, Arjmand Muir, Andrew Musso, Giovanni Myers, Robert Nagy, Laura E. Nakae, Susumu Nakanuma, Yasuni Nakatsura, Tetsuya Nattermann, Jacob Navarro, Victor Negro, Francesco Nelson, David Nelson, Kenrad Neuberger, James Neuschwander-Tetri, Brent Nevens, Frederik Newsome, Philip Ng, Irene Ng, Vicky Nguyen, Mindie Nieto, Natalia Nobili, Valerio Novelli, Gilnardo Odenthal, Margarete O’Doherty, Robert Ogretmen, Besim Ohdan, Hideki O’Leary, Jacqueline Olson, Jody Olynyk, John Omland, Lars Oresic, Matej Orlando, Ludovic Ortiga-Carvalho, T.M. Osburn, William Oshita, Akihiko Österreicher, Christoph Ostrow, J. Donald Ott, Melanie Ott, Michael Otterbein, Leo Oude Elferink, Ronald P. J.